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This article first appeared in the February 1999 issue of
Vegan.com.
Reprinted by permission.
Eight years ago, near the height of Britain's mad cow
epidemic, I took an acquaintance to an outdoor concert in
California. As we sat in the lawn seating area, waiting for
the band to take the stage, Julia fished a tin of mints out
of her purse. She offered me a mint, and I asked to check
the box to be sure it was vegan. She gave me one of her
scornful looks that she reserved for when she thought my
diet was losing touch with reality: "It's a breath
mint," she said, "of course it's vegan."
It was one of those unpleasant social situations that
vegans sometimes get into when they spend time with the
wrong people. I don't even like breath mints, vegan or not.
But I took Julia at her word and popped a mint in my mouth
to defuse the situation.
She put the tin onto our blanket. Several minutes later,
the band had still not taken the stage, so I casually looked
at the mint tin. On the label, the last ingredient was
gelatin. And another nearby label said "Imported from
Great Britain."
I didn't realize it then, but at that moment I joined the
list -- the list of people who may have been exposed to the
agent that causes mad cow disease and its deadly human
counterpart, new variant Creutzfeldt-Jakob Disease.
Scientists don't know if gelatin made from mad cows can pass
along the infection to pass along the infection, and the
probability that the 1/10 of a gram of gelatin I consumed
from a single mint could trigger an infection is highly
remote. Nevertheless, I immediately realized that I had
joined a very undesirable list and that there would be no
way to remove myself.
Thirteen years have passed since the first cows in Great
Britain began dying of Bovine Spongiform Encephalopathy (BSE).
The disease has generated countless headlines and time and
again entangled Britain in political and economic turmoil.
Already one Nobel Prize has been awarded for work done on
the disease. Yet for all the research and public debate
undertaken so far, the central question remains unanswered:
nobody has any idea how many people will die. Thanks to new
advances in medical testing, however, the people of Great
Britain are on the verge of learning the truth.
The truth may be much darker than feared. As far back as
the 1980s, leading microbiologist Richard Lacey warned that
Great Britain could lose an entire generation of people to
the BSE prion. The best evidence available suggests that the
average person in Great Britain has eaten over 70 meals
containing meat from infected cattle. Yet the British people
have been constantly encouraged by their government not to
worry about beef safety. Over the years, the government has
repeatedly proclaimed that human risks associated with beef
eating ranged from minimal to nonexistent.
The government's lack of action to discourage beef eating
has helped Britain's beef industry to recover from the mad
cow crisis. Right now, British farmers' unions and butchers
are lobbying hard to lift the government ban on T-Bone
steaks. Recently, a representative of the National Farmers'
Union said: "All the scientific evidence that has been
made public so far suggests that the risks from eating beef
on the bone are absolutely minuscule."
Such reassurances have won over much of the British
public because nobody has any idea how widely the disease
has spread. New variant Creutzfeldt-Jakob Disease (nvCJD) --
a deadly brain disorder that appears to be caused by the BSE
prion -- is notoriously hard to diagnose, especially in its
early stages. Until the past month or so, it was possible to
diagnose nvCJD only in well-advanced cases, and even then
all diagnosis were tentative because they were based on
changes in behavior. Only after the victim was dead or at
death's door could a brain sample can be taken to
conclusively reveal the damage of advanced nvCJD. The fact
that 40 people have died of nvCJD in Great Britain tells us
only that the BSE prion seems capable of infecting people.
The unanswered question is: will future deaths number in the
dozens or in the millions? Right now, it's anybody's guess.
The guessing game is about to end, however, and in the
next year or two scientists should have a clear idea of how
many Britons are carrying the prion. Although the prion
responsible for BSE and nvCJD causes damage exclusively to
brain tissue, it is known to show up elsewhere in the body.
Recently developed tests detect prions in the tonsil tissue
well before the first signs of mental degradation emerge.
According to the January 16 Lancet: "The find means it
may be possible in the next three years to establish if a
CJD time bomb is ticking within Britain's population."
Starting soon, every tonsil taken out in British
hospitals will be sent to health laboratories for testing.
Since British surgeons perform untold thousands of
tonsillectomies each year, the prion status of a significant
percentage of Britain's population is about to become known.
The new testing technology is forcing many scientists and
government officials to contemplate worst-case scenarios.
Already, in Britain's highest scientific circles, there is
serious discussion about keeping infection rates secret.
Moreover, some scientists are suggesting that test results
should be withheld even from people who have tested positive
for the prion.
New Scientist is one of the scientific community's most
highly regarded periodicals. A January 23 editorial comes
down firmly against telling people they have tested
positive:
For the moment, at least, there seems to be nothing an
individual will gain by knowing. There are no drugs that
prevent prions making mischief in humans, nor is there any
evidence that diet or exercise can improve your chances in
the way it might with a predisposition to heart disease.
And knowing that you carry the agent linked to nvCJD is
unlikely to help you to prepare for your
demise--especially if you don't know whether you have two
years left or 20.
The editorial is correct that, unlike with AIDS, there
may be no benefit in slowing the spread of the disease by
letting people know their status. Barring cannibalism,
prions appear unable to spread from one person to another,
even by sexual contact. Yet it's hard to believe that the
editorial writer really has the victim's best interests at
heart in arguing to keep test results hidden. Nobody doubts
that being told you've tested positive for nvCJD would be
terrifying news. But surely it would be even worse to go
through life carrying the prion, and never to learn the
truth until you seek help after developing symptoms of the
disease. In addition, scientists don't yet know if the
disease can be spread when an infected person donates blood
-- this alone would be compelling reason to track down and
inform anyone who tests positive.
The more likely reason that New Scientist wants to keep
all tests secret isn't out of concern for victims. It is to
prevent alarm. The editorial continues: "...even a hint
that tens of thousands of Britons could be incubating nvCJD
could spread panic."
Here, the logic of the New Scientist editorial breaks
down entirely. If the surgery tests reveals a large
percentage of Britons as being infected, attempts to keep
this information restricted to the hands of scientists would
demand a cover-up of impossible proportions. Indeed, if the
tonsil tests reveal Britain is facing catastrophe, the only
way to keep hysteria from overwhelming Britain is to make
the best and most accurate information public -- and to do
it as quickly as possible through the most reliable sources.
One way or another, if vast numbers of people are infected,
word will get out. And panic would undoubtedly be less
severe if the story breaks in the London Times instead of in
the Drudge Report.
***
While Britain's government and beef industry still say
there's little or no reason to worry, some American
officials are considering the possibility that Britain's
absolute worst-case scenario is about to play out. Under
this scenario, a single meal made from an infected animal
would be enough to infect a person with nvCJD. Such a
scenario would bring a death sentence for anyone in Britain
who has eaten a contaminated hamburger since 1985.
In the US, policy-makers are taking this scenario
seriously&emdash;so seriously that America's blood
donation regulations may soon be drastically modified. By
next year, any person who has set foot in England since 1985
may be forbidden from donating blood. It's by no means
certain that these tough new regulations will be put into
place, but they do show how seriously American scientists
are regarding the BSE problem.
Even if tough new blood regulations are swiftly put in
place, Americans should not yet rest easy because there are
some preliminary signs that at least one new type of prion
has already appeared on US shores. The US has taken some
action to see that the practice that kicked off Britain's
mad cow epidemic won't happen here. Since June of 1997,
cattle-to-cattle feeding has been banned in the US. But it
is still perfectly legal to feed one type of farm animal,
say ground-up cattle by-products, to another type of animal,
say pigs. And as long as farm animals are being fed back to
other farm animals, there is the possibility of creating a
widespread prion-related outbreak that ultimately reaches
consumers.
During the past year, seven CJD cases have appeared in
Utah, while statistically this rare disease should attack
just two people from Utah in any given year. It's still too
early to know if the Utah cases are merely a statistical
aberration. Even if prions have found their way into the
food supply, it's also much to early to blame commercial
meat products for the outbreak.
What is known, however, is that at least one of the cases
involved a man far younger than is typical among
garden-variety CJD. Most cases of CJD typically involve
people well past the age of fifty, whereas the new variant
linked to Great Britain's mad cow epidemic commonly strikes
people from their teens to early 30s.
Doug McEwen, a 30-year-old husband and father of two, is
now close to death from CJD. And while the damage in his
brain sample lacks the signature of Britain's New Variant
CJD, the fact that CJD has appeared in someone raises
troubling concerns about about America's prion status. Six
months ago McEwen was big, fit, and healthy. But signs of
trouble began to emerge early last summer, starting when he
forgot the spelling of his wife's name. Last July, away on a
business trip, he needed to call home but forgot both his
phone number and the spelling of his last name.
Today, McEwen is near death and hovers in and out of
consciousness. Pinning a cause on McEwen's illness, along
with the six other Utah CJD cases, is all but impossible.
McEwen was a hunter, so there is a possibility that he ate
meat from a deer suffering from (prion-related) Chronic
Wasting Disease. He also served as a Mormon missionary up in
Canada, where it's possible that he was served meat or fish
that was contaminated with prions. It's also still
impossible to rule out that McEwen and the other Utah
residents were infected through some form of contaminated
beef, pork, chicken, or fish that was produced and sold in
Utah.
The lessons to take from Great Britain are at once
troubling and fairly obvious. The place to start is with a
little humility; realizing that there is a tremendous amount
about prions that we don't yet understand. We should start
by banning all feeding of livestock to livestock in the
United States, at least until we know more about prions.
The reason BSE was able to spread throughout Britain is
that the government put the burden of proof on health
advocates instead of upon the beef industry. By doing what
is best for the cattle industry, the leaders of Great
Britain have betrayed the public, and exposed huge numbers
of people to the possibility of a wretched and undignified
death. What we are about to witness in Great Britain may
involve fewer than a hundred deaths or it may become the
first great horror of the next century. An even greater
horror would be if the rest of the world fails to learn from
Britain's mistakes, and the tragedy is repeated elsewhere.
Erik Marcus is the author of Vegan: The New Ethics of
Eating
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